The comprehensive Institutional Scientific Report is published on a yearly basis and contains a display of the scientific contributions originating intramurally from basic as well as clinical research activities. The Institutional Scientifc Report is an important tool for the overall visibility of the scientic activities of the San Raffaele Scientific Institute. It is a user-friendly, logically organised description of the entire body of research carried out intramurally, which can be accessed both by researchers and by lay people.