The epidemiology and data management core was established with the aim of providing methodological support to investigator-initiated clinical research projects within the Department of Immunology with special regards to those within the Diabetes Research Institute (DRI). Priority of this core are the translational research projects developed within the San Raffaele Scientific Institute. The support offered by this core to investigators include consultation on study design, data collection and validation, development and validation of ad hoc questionnaires, statistical analyses and data presentation. Furthermore the core collaborates with investigators in the preparation of grant proposal and scientific manuscripts.